Cryptic crossword clue
Fasten on a tree 8

The most common and most likely answer to this crossword clue is the 8 letter word CINCHONA

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The cryptic/wordplay part
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This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
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What does CINCHONA mean?

CINCHONA noun
  1. A tree or shrub of the genus Cinchona, native to the Andes in South America but since widely cultivated in Indonesia and India as well for its medicinal bark.
  2. The bark of these plants, which yield quinine and other alkaloids useful in reducing fevers and particularly in combatting malaria.
  3. Any medicine chiefly composed of the prepared bark of these plants.

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