The most common and most likely answer to this crossword clue is the 6 letter word CLOTHO
I've seen this crossword clue in Independent
C
L
O
T
H
O
More clues leading to the result CLOTHO
- Expression of surprise after fool gets goddess
- Reluctant to intervene in company’s Fate?
- Fate is cold and reluctant before love
- Fate of dimwit accompanied by some laughter
- Fate of idiot — how interminable!
- Fate could let out thread holding our origins
- Fate‘s woven threads, central character from mythology
- Fate of idiot with hope half gone
- Fate? One’s limited in preference when there’s no ice
- Fate of Charlie on hold
Buddy explains!

The straight part
We know that "Fate" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case fate = clotho.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.