The most common and most likely answer to this crossword clue is the 8 letter word OVERDOSE
I've seen this crossword clue in The Daily Telegraph
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More clues leading to the result OVERDOSE
- Finished parties on ecstasy, too much of it perhaps
- Old poem about party excess that may be fatal
- Fate of one who didn’t take just what the doctor ordered
- It could make one ever so zonked going round party!
- . Dove rose awkwardly — too much of drug, perhaps
- Exaggerate and vacuously state what a junkie or suicidal fellow might do
- After lover is decapitated, does punk shoot up too much?
Buddy explains!

The straight part
We know that "Fate of one who didn’t take just what the doctor ordered" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case fate of one who didn’t take just what the doctor ordered = overdose.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does OVERDOSE mean?
OVERDOSE noun- An excessive and dangerous dose of a drug.
- To dose excessively, to take an overdose.
- To indulge in something excessively.
- To dose to excess; to give an overdose, or too many doses, to.