The most common and most likely answer to this crossword clue is the 5 letter word KARMA
I've seen this crossword clue in Financial Times
K
A
R
M
A
More clues leading to the result KARMA
- King and Ace encapsulating power and fate
- Consequence of initiating kettling, as rioters may attack
- VP leaving Los Angeles embracing the culmination of her destiny
- Time to avoid backing US railways – there’s fate to be suffered
- Suffering regular losses, retired farmer backs fate
- Fate of soul with a jolly heart
- Sounding more relaxed with one’s destiny
- Buddhist concept that could make you more relaxed, reportedly
- Discussed more peaceful destiny
- Awful mark, then good one — that’s fate
Buddy explains!

The straight part
We know that "Fate" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case fate = karma.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does KARMA mean?
KARMA noun- The sum total of a person's actions, which determine the person's next incarnation in samsara, the cycle of death and rebirth.
- A force or law of nature which causes one to reap what one sows; destiny; fate.
- A distinctive feeling, aura, or atmosphere.
- (Reddit) A score assigned to a user of a discussion forum, indicating the popularity of their posts with other users.