The most common and most likely answer to this crossword clue is the 9 letter word CARBUNCLE
C
A
R
B
U
N
C
L
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More clues leading to the result CARBUNCLE
- Worry eating cake, about 50 stone
- Short couple returning pawnbroker's gem
- Vehicle black and dirty, not an attractive gem?
- A source of energy and relative growth
- Painful thing seeing a couple almost knocked over by relative
- Source of energy for relative with skin problem
- Vehicle black and dirty not an eyesore
- Spot oversight, arresting knight in seedy club
- Fattening food’s given relative inflammation
- Boil sugar for one family member.
Buddy explains!

The straight part
We know that "inflammation" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case inflammation = carbuncle.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does CARBUNCLE mean?
CARBUNCLE noun- A deep-red or fiery colored garnet or other dark red precious stone, especially when cut cabochon.
- A charge or bearing supposed to represent the precious stone, with eight sceptres or staves radiating from a common centre; an escarbuncle.
- An abscess larger than a boil, usually with one or more openings draining pus onto the skin. It is usually caused by bacterial infection.
- An unpopular or ugly building; an eyesore.