The most common and most likely answer to this crossword clue is the 2 plus 2 plus 1 plus 4 plus 5 letter word BE IN A COLD SWEAT
B
E
I
N
A
C
O
L
D
S
W
E
A
T
Buddy explains!

The straight part
We know that "Fear of" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case fear of = be in a cold sweat.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.