Cryptic crossword clue
Fed up and gloomy from loss of honour 11

The most common and most likely answer to this crossword clue is the 11 letter word DEFLOWERING

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Buddy explains!

The straight part
We know that "loss of honour" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case loss of honour = deflowering.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DEFLOWERING mean?

DEFLOWERING verb
  1. To take the virginity of (somebody), especially a woman or girl.
  2. To deprive of flowers.
  3. To deprive of grace and beauty.
DEFLOWERING noun
  1. The breaking of the hymen of a virgin.

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