Cryptic crossword clue
Fed up with being exploited and rendered ineffective 7

The most common and most likely answer to this crossword clue is the 7 letter word DEFUSED

I've seen this crossword clue in The Daily Telegraph
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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
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What does DEFUSED mean?

DEFUSED verb
  1. To remove the fuse from (a bomb, etc.).
  2. To make less dangerous, tense, or hostile.
DEFUSED verb
  1. To disorder; to make shapeless.

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