Cryptic crossword clue
Feel the loss of one’s wife 6

The most common and most likely answer to this crossword clue is the 6 letter word MISSIS

I've seen this crossword clue in Financial Times
M
I
S
S
I
S

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MISSIS mean?

MISSIS noun
  1. Wife or girlfriend.
  2. Term of address for a woman.

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