The most common and most likely answer to this crossword clue is the 9 letter word CATALONIA
C
A
T
A
L
O
N
I
A
More clues leading to the result CATALONIA
- Animal, mostly solitary, primarily inhabiting a region of Spain
- A cat and a lion wandering round Spanish territory
- Welsh band in state of stupor, getting lost for a short time in Spanish district
- Look to invade Sicilian city, European territory
- Left wearing a coat in a rocky region of Spain
- Regionās irregular act, unilaterally leaving Spain, leads to immediate arrests
- Security set-up arrests a nipper somewhere in Spain
- A stock of cards collected by agents in Spanish region
- Agents to guard a chess champion, playing in region of Spain
- Feline, a lion, roaming a region of Spain
Buddy explains!

The straight part
We know that "region of Spain" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case region of spain = catalonia.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.