Cryptic crossword clue
Female I spotted in study, poet’s lady friend 10

The most common and most likely answer to this crossword clue is the 10 letter word CONFIDANTE

I've seen this crossword clue in The Sunday Telegraph
C
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N
F
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Buddy explains!

The straight part
We know that "lady friend" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case lady friend = confidante.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CONFIDANTE mean?

CONFIDANTE noun
  1. A female confidant.
  2. A type of settee having a seat at each end at right angles to the main seats.

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