Cryptic crossword clue
Female minister’s in top role 12

The most common and most likely answer to this crossword clue is the 12 letter word DIRECTORSHIP

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Buddy explains!

The straight part
We know that "top role" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case top role = directorship.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DIRECTORSHIP mean?

DIRECTORSHIP noun
  1. The office of a director; a directorate

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