Cryptic crossword clue
Female sick, not going to make it 7

The most common and most likely answer to this crossword clue is the 7 letter word FAILING

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Buddy explains!

The straight part
We know that "not going to make it" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case not going to make it = failing.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does FAILING mean?

FAILING verb
  1. To be unsuccessful.
  2. Not to achieve a particular stated goal. (Usage note: The direct object of this word is usually an infinitive.)
  3. To neglect.
  4. Of a machine, etc.: to cease to operate correctly.
  5. To be wanting to, to be insufficient for, to disappoint, to desert.
  6. To receive one or more non-passing grades in academic pursuits.
  7. To give a student a non-passing grade in an academic endeavour.
  8. To miss attaining; to lose.
  9. To be wanting; to fall short; to be or become deficient in any measure or degree up to total absence.
  10. To be affected with want; to come short; to lack; to be deficient or unprovided; used with of.
  11. To fall away; to become diminished; to decline; to decay; to sink.
  12. To deteriorate in respect to vigour, activity, resources, etc.; to become weaker.
  13. To perish; to die; used of a person.
  14. To err in judgment; to be mistaken.
  15. To become unable to meet one's engagements; especially, to be unable to pay one's debts or discharge one's business obligation; to become bankrupt or insolvent.
FAILING noun
  1. Weakness; defect
FAILING preposition
  1. If the preferred or prior option is not possible

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