Cryptic crossword clue
Fine artist occupying minister’s house being obstinate 10

The most common and most likely answer to this crossword clue is the 10 letter word REFRACTORY

I've seen this crossword clue in Independent
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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does REFRACTORY mean?

REFRACTORY noun
  1. A material or piece of material, such as a brick, that has a very high melting point.
REFRACTORY adjective
  1. Obstinate and unruly; strongly opposed to something.
  2. Not affected by great heat.
  3. Difficult to treat.
  4. Incapable of registering a reaction or stimulus.

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