Cryptic crossword clue
Fine centre running, about to break through obstruction 12

The most common and most likely answer to this crossword clue is the 12 letter word INTERFERENCE

I've seen this crossword clue in The Daily Telegraph
I
N
T
E
R
F
E
R
E
N
C
E

More clues leading to the result INTERFERENCE

Buddy explains!

The straight part
We know that "obstruction" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case obstruction = interference.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does INTERFERENCE mean?

INTERFERENCE noun
  1. The act of interfering with something, or something that interferes.
  2. The illegal obstruction of an opponent in some ball games.
  3. An effect caused by the superposition of two systems of waves.
  4. A distortion on a broadcast signal due to atmospheric or other effects.
  5. In United States patent law, an inter partes proceeding to determine the priority issues of multiple patent applications; a priority contest.
  6. The interruption of the line between an attacked piece and its defender by sacrificially interposing a piece.
  7. The situation where a person who knows two languages inappropriately transfers lexical items or structures from one to the other.

Latest crossword clues with full explanations