Cryptic crossword clue
Firm joins US university engaging a thousand in effect 6

The most common and most likely answer to this crossword clue is the 6 letter word COMMIT

I've seen this crossword clue in The Daily Telegraph
C
O
M
M
I
T

Buddy explains!

The straight part
We know that "effect" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case effect = commit.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does COMMIT mean?

COMMIT noun
  1. The act of committing (e.g. a database transaction or source code into a source control repository), making it a permanent change.
COMMIT verb
  1. To give in trust; to put into charge or keeping; to entrust; to consign; used with to or formerly unto.
  2. To put in charge of a jailer; to imprison.
  3. To have (a person) enter an establishment, such as a hospital or asylum, as a patient.
  4. To do (something bad); to perpetrate, as a crime, sin, or fault.
  5. To join a contest; to match; followed by with.
  6. To pledge or bind; to compromise, expose, or endanger by some decisive act or preliminary step. (Traditionally used only reflexively but now also without oneself etc.)
  7. To make a set of changes permanent.
  8. (Latinism) To confound.
  9. To commit an offence; especially, to fornicate.
  10. To be committed or perpetrated; to take place; to occur.

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