The most common and most likely answer to this crossword clue is the 11 letter word TERMINATION
I've seen this crossword clue in The Daily Telegraph
T
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More clues leading to the result TERMINATION
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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does TERMINATION mean?
TERMINATION noun- The process of terminating or the state of being terminated.
- The process of firing an employee; ending one's employment at a business for any reason.
- An end in time; a conclusion.
- An end in space; an edge or limit.
- An outcome or result.
- The last part of a word; an ending, a desinence; a suffix.
- An induced abortion.
- A word, a term.
- The ending up of a polypeptid chain.