Cryptic crossword clue
Fool North with one trump initially, then with 22 being discarded 6

The most common and most likely answer to this crossword clue is the 6 letter word NITWIT

I've seen this crossword clue in Financial Times
N
I
T
W
I
T


Buddy explains!

The straight part
We know that "Fo/o/l" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case fo/o/l = nitwit.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does NITWIT mean?

NITWIT noun
  1. A scatterbrained or stupid person.

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