Cryptic crossword clue
For each act of separation tenacity is the answer 12

The most common and most likely answer to this crossword clue is the 12 letter word PERSEVERANCE

I've seen this crossword clue in Financial Times
P
E
R
S
E
V
E
R
A
N
C
E


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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PERSEVERANCE mean?

PERSEVERANCE noun
  1. Continuing in a course of action without regard to discouragement, opposition or previous failure.

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