The most common and most likely answer to this crossword clue is the 2 plus 6 plus 2 letter word IN FAVOUR OF
I've seen this crossword clue in The Guardian
I
N
F
A
V
O
U
R
O
F
Buddy explains!
The straight part
We know that "For" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case for = in favour of.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.