Cryptic crossword clue
Foremost of pupils in an exam must be this? 6

The most common and most likely answer to this crossword clue is the 6 letter word APTEST

I've seen this crossword clue in The Guardian
A
P
T
E
S
T


Buddy explains!

The straight part
We know that "Foremost of pupils in an exam must be this?" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case foremost of pupils in an exam must be this? = aptest.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does APTEST mean?

APTEST adjective
  1. Suitable; appropriate; fit or fitted; suited.
  2. (of persons or things) Having a habitual tendency; habitually liable or likely; disposed towards.
  3. Ready; especially fitted or qualified (to do something); quick to learn.

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