Cryptic crossword clue
Former president getting head from Monica — a second short spell in White House 25

The most common and most likely answer to this crossword clue is the 10 letter word BUSHMASTER

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "25" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case 25 = bushmaster.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does BUSHMASTER mean?

BUSHMASTER noun
  1. A venomous pit viper, Lachesis muta, from tropical America

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