Cryptic crossword clue
Fortune in very large inheritance, ultimately 4

The most common and most likely answer to this crossword clue is the 4 letter word FATE

I've seen this crossword clue in Financial Times
F
A
T
E


Buddy explains!

The straight part
We know that "Fortune" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case fortune = fate.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does FATE mean?

FATE noun
  1. The presumed cause, force, principle, or divine will that predetermines events.
  2. The effect, consequence, outcome, or inevitable events predetermined by this cause.
  3. An event or a situation which is inevitable in the fullness of time.
  4. Destiny; often with a connotation of death, ruin, misfortune, etc.
  5. Alternative letter-case form of Fate (one of the goddesses said to control the destiny of human beings).
FATE verb
  1. To foreordain or predetermine, to make inevitable.

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