The most common and most likely answer to this crossword clue is the 3 plus 2 letter word SET UP
I've seen this crossword clue in The Times
S
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More clues leading to the result SET UP
Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SET UP mean?
SET UP noun- Equipment designed for a particular purpose; an apparatus.
- The fashion in which something is organized or arranged.
- A situation orchestrated to frame someone; a covert effort to place the blame on somebody.
- An installer.
- (operations) The process of arranging resources for performing a specific operation, as a run of a particular product.
- The tendency of persistent wind to produce higher water levels at the downwind shore of a body of water and lower at the upwind shore.