Cryptic crossword clue
Four in a Republican cartel reaching destination 8

The most common and most likely answer to this crossword clue is the 8 letter word ARRIVING

I've seen this crossword clue in Independent
A
R
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Buddy explains!

The straight part
We know that "reaching destination" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case reaching destination = arriving.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ARRIVING mean?

ARRIVING verb
  1. To reach; to get to a certain place.
  2. To obtain a level of success or fame; to succeed.
  3. To come; said of time.
  4. To happen or occur.
  5. To reach; to come to.
  6. To bring to shore.

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