Cryptic crossword clue
Freaks of nature: mongrels ain’t regularly included 7

The most common and most likely answer to this crossword clue is the 7 letter word MUTANTS

M
U
T
A
N
T
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The straight part
We know that "Freaks of nature" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case freaks of nature = mutants.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MUTANTS mean?

MUTANTS noun
  1. Something which has mutated, which has one or more new characteristics from a mutation.
  2. Someone or something that seems strange, abnormal, or bizarre.
MUTANTS noun
  1. An object in a program that serves as a lock, used to negotiate mutual exclusion among threads.

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