The most common and most likely answer to this crossword clue is the 8 letter word DEGREASE
I've seen this crossword clue in The Daily Telegraph
D
E
G
R
E
A
S
E
More clues leading to the result DEGREASE
Buddy explains!

The straight part
We know that "Free from grime" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case free from grime = degrease.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DEGREASE mean?
DEGREASE verb- To remove grease from something.