Cryptic crossword clue
Fresh concern in place with vermin returning 5-2

The most common and most likely answer to this crossword clue is the 8 letter word START-UP

I've seen this crossword clue in The Guardian
S
T
A
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T
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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does START-UP mean?

START-UP noun
  1. The act or process of starting a process or machine.
  2. A new company or organization or business venture designed for rapid growth.

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