Cryptic crossword clue
Gamble, without a note, and with hesitation, for an instrument 8

The most common and most likely answer to this crossword clue is the 8 letter word SPECULUM

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Buddy explains!

The straight part
We know that "instrument" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case instrument = speculum.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SPECULUM mean?

SPECULUM noun
  1. A medical instrument used during an examination to dilate an orifice.
  2. A mirror, especially one used in a telescope.
  3. A bright, lustrous patch of colour found on the wings of ducks and some other birds, usually situated on the distal portions of the secondary quills, and much more brilliant in the adult male than in the female.
  4. A lookout place.

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