The most common and most likely answer to this crossword clue is the 8 letter word LACROSSE
I've seen this crossword clue in The Times
L
A
C
R
O
S
S
E
More clues leading to the result LACROSSE
- At Roland-Garros, the shot scores in game
- Game casserole almost ruined
- Explorer in what may be tied game
- In Pakistan a vast number grew up round second game
- Sport in Los Angeles annoyed English
- Game lady, not half, scores freely
- Foreign article covering a sport
- Game scores adjusted, City at the top
- The French irritated by English game.
- Game left over at end of table
Buddy explains!

The straight part
We know that "Game" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case game = lacrosse.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does LACROSSE mean?
LACROSSE noun- A sport played on a field between two opposing teams using sticks (crosses) and a ball, whereby one team defeats the other by achieving a higher score by scoring goals within the allotted time.