The most common and most likely answer to this crossword clue is the 8 plus 6 letter word CONTRACT BRIDGE
I've seen this crossword clue in The Daily Telegraph
C
O
N
T
R
A
C
T
B
R
I
D
G
E
More clues leading to the result CONTRACT BRIDGE
- Instruction for nose job, perhaps, that requires two pairs of hands
- Study area north of river crossing maybe in game
- Game of catch crossing over the road?
- Cross after catch in card game
- Catch cross in game
- Batting record broken by Cheshire’s opener in this game
- Get cross in game
- Come together on part of ship for a game
- & 22a It involves tricks to tighten with spanner
- Game of catch, then rest
Buddy explains!
The straight part
We know that "Game" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case game = contract bridge.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.