The most common and most likely answer to this crossword clue is the 6 letter word VACUUM
I've seen this crossword clue in The Daily Telegraph
V
A
C
U
U
M
More clues leading to the result VACUUM
- There’s nothing in it for cleaner
- Account to use when talking through ‘very little money’? There’s nothing in it!
- See a copper I don’t know clean the carpet?
- Gap holiday before university with mother going topless!
- Clean area providing free space
- There’s a natural abhorrence for such a cleaner
- Abhorred by nature?
- Emptiness of holiday for two of you at beginning of May
- It sucks
- Empty space for home appliance
Buddy explains!

The straight part
We know that "Gap" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case gap = vacuum.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does VACUUM mean?
VACUUM noun- A region of space that contains no matter.
- (plural only "vacuums") A vacuum cleaner.
- The condition of rarefaction, or reduction of pressure below that of the atmosphere, in a vessel, such as the condenser of a steam engine, which is nearly exhausted of air or steam, etc.
- A spacetime having tensors of zero magnitude
- To clean (something) with a vacuum cleaner.
- To use a vacuum cleaner.
- To optimise a database or database table by physically removing deleted tuples.