The most common and most likely answer to this crossword clue is the 7 letter word SYNAPSE
I've seen this crossword clue in The Guardian
S
Y
N
A
P
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E
More clues leading to the result SYNAPSE
- Pens, say, recreated a connection in the mind
- Space between cells wrong, programs declared
- Photos including unknown drug in a feature of the nervous system
- Pens, say – surprisingly integral part of communication network
- Gap in head painlessly fixed, I’ll set out
- Cy sleeps soundly, which allows a nervy connection
- Whatever in clairvoyance’s recalled mental connection?
Buddy explains!

The straight part
We know that "Gap in head" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case gap in head = synapse.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SYNAPSE mean?
SYNAPSE noun- The junction between the terminal of a neuron and either another neuron or a muscle or gland cell, over which nerve impulses pass.
- To form a synapse.
- To undergo synapsis.