Cryptic crossword clue
Genealogical science for the lady’s almost entirely uninteresting 8

The most common and most likely answer to this crossword clue is the 8 letter word HERALDRY

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Buddy explains!

The straight part
We know that "Genealogical science" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case genealogical science = heraldry.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does HERALDRY mean?

HERALDRY noun
  1. The profession or art of devising, granting and blazoning coats of arms, tracing genealogies and ruling on questions of protocol or rank.
  2. An armorial ensign along with its history and description.
  3. Pageantry.

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