Cryptic crossword clue
Get tough and cross if you’re eating it 6

The most common and most likely answer to this crossword clue is the 6 letter word OSSIFY

I've seen this crossword clue in Financial Times
O
S
S
I
F
Y


Buddy explains!

The straight part
We know that "Get tough" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case get tough = ossify.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does OSSIFY mean?

OSSIFY verb
  1. To transform (or cause to transform) from a softer animal substance into bone; particularly the processes of growth in humans and animals.
  2. (animate) To become (or cause to become) inflexible and rigid in habits or opinions.
  3. (inanimate) To grow (or cause to grow) formulaic and permanent.
  4. To calcify.

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