The most common and most likely answer to this crossword clue is the 9 letter word DEPRESSES
I've seen this crossword clue in The Guardian
D
E
P
R
E
S
S
E
S
Buddy explains!

The straight part
We know that "Gets/holds down" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case gets/holds down = depresses.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DEPRESSES mean?
DEPRESSES verb- To press down.
- To make depressed, sad or bored.
- To cause a depression or a decrease in parts of the economy.
- To bring down or humble; to abase (pride, etc.).
- To reduce (an equation) in a lower degree.