Cryptic crossword clue
Getting dangerously full, feed on substitute mainly, refined and graded 14

The most common and most likely answer to this crossword clue is the 14 letter word SUPERSATURATED

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Buddy explains!

The straight part
We know that "Getting dangerously full" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case getting dangerously full = supersaturated.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SUPERSATURATED mean?

SUPERSATURATED verb
  1. To cause a solution to have more solute dissolved in it than it can stably contain at current conditions.
SUPERSATURATED adjective
  1. (of a solution) More concentrated than is normally possible.
  2. (of a vapor) Having a vapor pressure higher than is normally possible.

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