The most common and most likely answer to this crossword clue is the 5 letter word COATS
I've seen this crossword clue in The Times
C
O
A
T
S
More clues leading to the result COATS
Buddy explains!

The straight part
We know that "clothes" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case clothes = coats.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does COATS mean?
COATS noun- An outer garment covering the upper torso and arms.Wp
- A covering of material, such as paint.Wp
- The fur or feathers covering an animal's skin.Wp
- Canvas painted with thick tar and secured round a mast or bowsprit to prevent water running down the sides into the hold (now made of rubber or leather).
- A petticoat.
- The habit or vesture of an order of men, indicating the order or office; cloth.
- A coat of arms.Wp
- A coat card.
- To cover with a coating of some material.
- To cover like a coat.
- To clothe.