Cryptic crossword clue
Girl is after fish causing disease 10

The most common and most likely answer to this crossword clue is the 10 letter word SALMONELLA

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "causing disease" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case causing disease = salmonella.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SALMONELLA mean?

SALMONELLA noun
  1. Any of several rod-shaped bacteria, of the genus Salmonella, that cause food poisoning and other diseases

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