The most common and most likely answer to this crossword clue is the 5 letter word SUSAN
I've seen this crossword clue in The Daily Telegraph
S
U
S
A
N
More clues leading to the result SUSAN
- Potentially miss appeal appearing in paper
- Girl from South America – Republican’s ‘tail’
- Girl from South Africa featured in tabloid …
- Girl takes Poles round America
- Girl from South America, west of Nicaragua
- Name of star oddly featuring in tabloid
- Odd bits of song about country girl
- Girl from America, into heavy metal
- Name of “Miss America” featured in every other song
- “Lazy” girl star going around South America
Buddy explains!

The straight part
We know that "Girl" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case girl = susan.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.