The most common and most likely answer to this crossword clue is the 6 letter word DEVOTE
D
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V
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More clues leading to the result DEVOTE
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The straight part
We know that "Give" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case give = devote.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DEVOTE mean?
DEVOTE verb- To give one's time, focus one's efforts, commit oneself, etc. entirely for, on, or to a certain matter
- To consign over; to doom
- To execrate; to curse
- Devoted; addicted; devout