Cryptic crossword clue
Give some bottles a rinse — there’s poison there 5

The most common and most likely answer to this crossword clue is the 5 letter word SARIN

I've seen this crossword clue in The Guardian
S
A
R
I
N

Buddy explains!

The straight part
We know that "there’s poison there /there’s poison there" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case there’s poison there /there’s poison there = sarin.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SARIN mean?

SARIN noun
  1. The neurotoxin O-isopropyl methylphosphonofluoridate, used as a chemical weapon.

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