Cryptic crossword clue
Gives new life to friends after endless panic 8

The most common and most likely answer to this crossword clue is the 8 letter word ANIMATES

I've seen this crossword clue in The Daily Telegraph
A
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Buddy explains!

The straight part
We know that "Gives new life to" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case gives new life to = animates.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ANIMATES mean?

ANIMATES verb
  1. To impart motion or the appearance of motion to.
  2. To give spirit or vigour to; to stimulate or enliven; to inspirit.

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