Cryptic crossword clue
Gloomy note disrupted study of insects 10

The most common and most likely answer to this crossword clue is the 10 letter word ENTOMOLOGY

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Buddy explains!

The straight part
We know that "study of insects" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case study of insects = entomology.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ENTOMOLOGY mean?

ENTOMOLOGY noun
  1. The scientific study of insects, and (informally) of other arthropods (and occasionally other invertebrates).

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