The most common and most likely answer to this crossword clue is the 7 letter word GOUACHE
I've seen this crossword clue in Financial Times
G
O
U
A
C
H
E
More clues leading to the result GOUACHE
Buddy explains!

The straight part
We know that "work" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case work = gouache.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does GOUACHE mean?
GOUACHE noun- A thick, opaque watercolour paint made with gum containing an inert white pigment to make it opaque.
- A painting made with this paint.