Cryptic crossword clue
Going off course, runs into the remaining 8

The most common and most likely answer to this crossword clue is the 8 letter word STRAYING

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Buddy explains!

The straight part
We know that "Going off course" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case going off course = straying.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does STRAYING mean?

STRAYING verb
  1. To wander, as from a direct course; to deviate, or go out of the way.
  2. To wander from one's limits; to rove or roam at large; to go astray.
  3. To wander from the path of duty or rectitude; to err.
  4. To cause to stray.
STRAYING noun
  1. The act of one who strays; deviation or sin - often sexual infidelity.

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