Cryptic crossword clue
Gone astray, I have picked up old clothes 8

The most common and most likely answer to this crossword clue is the 8 letter word DEVIATED

I've seen this crossword clue in The Guardian
D
E
V
I
A
T
E
D

Buddy explains!

The straight part
We know that "Gone astray" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case gone astray = deviated.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DEVIATED mean?

DEVIATED verb
  1. To go off course from; to change course; to change plans.
  2. To fall outside of, or part from, some norm; to stray.
  3. To cause to diverge.

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