Cryptic crossword clue
   Graduate leaves large church compound 6

The most common and most likely answer to this crossword clue is the 6 letter word SILICA

I've seen this crossword clue in Independent
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Buddy explains!

The straight part
We know that "compound" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case compound = silica.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SILICA mean?

SILICA noun
  1. Silicon dioxide.
  2. Any of the silica group of the silicate minerals.

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