Cryptic crossword clue
Grand girl played in London’s East End? 6

The most common and most likely answer to this crossword clue is the 6 letter word JOANNA

J
O
A
N
N
A

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does JOANNA mean?

JOANNA noun
  1. (often "old joanna") A piano.

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