Cryptic crossword clue
Groggy metaphysician discards ripped panty material resulting in circulation problem 8

The most common and most likely answer to this crossword clue is the 8 letter word ISCHEMIA

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Buddy explains!

The straight part
We know that "circulation problem" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case circulation problem = ischemia.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ISCHEMIA mean?

ISCHEMIA noun
  1. Local disturbance in blood circulation due to mechanical obstruction of the blood supply (vasoconstriction, thrombosis or embolism).

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